Article
Analysis of anesthetic action on the potassium channels of the Shaker mutant of Drosophila.
Annals of the New York Academy of Sciences - 1 Jan 1991
Tinklenberg J A, Segal I S, Guo T Z, Maze M
Abstract excerpt
Recent evidence suggest that exposure to volatile anesthetic agents causes a change in conductance through an undelineated potassium channel. With recently developed genetic and molecular techniques the Drosophila melanogaster (D.m.) genome can be manipulated to study the role that potassium ion channel function plays in anesthetic action. The IA potassium channel is encoded by the Shaker (Sh) locus on the X...
Topics
- Animals
- Drosophila melanogaster
- Hot Temperature
- Isoflurane
- Mutation
- Potassium Channels
- X Chromosome