Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A voltage-clamp analysis of gene-dosage effects of the Shaker locus on larval muscle potassium currents in Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Apr 1990

Haugland F N, Wu C F

Abstract excerpt

Mutations of the Shaker (Sh) locus of Drosophila reduce, eliminate, or otherwise alter a transient potassium current, IA, in muscle. Recent molecular studies indicate that the Sh locus produces several proteins by alternative splicing, but the relationships of the variety of Sh gene products to IA channels in the various excitable membranes still remain to be determined. In Drosophila, many enzymes have been...

Topics

Aneuploidy
Animals
Chromosome Mapping
Drosophila melanogaster
Electrophysiology
Heterozygote
Homozygote
Larva
Muscles
Mutation
Potassium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Biosynthesis

Source

Open in PubMed Open full text

Identifiers

PMID: 2109786
PMCID: PMC6570215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2109786-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A voltage-clamp analysis of gene-dosage effects of the Shaker locus on larval muscle potassium currents in Drosophila.PMID 2109786Read ↗

Molecular basis of altered excitability in Shaker mutants of Drosophila melanogaster.Semantic proximity Read ↗

Genetic modification of potassium channels in Drosophila Shaker mutants.Semantic proximity Read ↗

Genetic analysis of the Shaker gene complex of Drosophila melanogaster.Semantic proximity Read ↗

Alteration of potassium channel gating: molecular analysis of the Drosophila Sh5 mutation.Semantic proximity Read ↗

Functional interactions between the gene tetanic and the Shaker gene complex of Drosophila.Semantic proximity Read ↗

Modulation of different K+ currents in Drosophila: a hypothetical role for the Eag subunit in multimeric K+ channels.Semantic proximity Read ↗

The Drosophila Shaker gene codes for a distinctive K+ current in a subset of neurons.Semantic proximity Read ↗

Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives.Semantic proximity Read ↗

Analysis of anesthetic action on the potassium channels of the Shaker mutant of Drosophila.Semantic proximity Read ↗

Alteration of four identified K+ currents in Drosophila muscle by mutations in eag.Semantic proximity Read ↗

Diverse expression and distribution of Shaker potassium channels during the development of the Drosophila nervous system.Semantic proximity Read ↗

The role of the divergent amino and carboxyl domains on the inactivation properties of potassium channels derived from the Shaker gene of Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.