Article
Association between C677T and A1298C MTHFR gene polymorphism and nonsyndromic orofacial clefts in the Turkish population: a case-parent study.
The Turkish journal of pediatrics - 1 Jan 2000
Semiç-Jusufagiç Aida, Bircan Rıfat, Çelebiler Özhan, Erdim Melike, Akarsu Nurten, Elçioğlu Nursel H
Abstract excerpt
Two common MTHFR gene polymorphisms (C677T and A1298C) have been implicated in the etiology of nonsyndromic cleft lip/palate (nsCL/P). To investigate the genotype association among nsCL/P in the Turkish population, 56 case-parent trios were recruited into the study. Genotype frequencies were compared to two groups of controls from the same population. A total of 46 case-parent trios were included in transmission...
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