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Article

Methylenetetrahydrofolate reductase C677T polymorphism is not associated with the risk of nonsyndromic cleft lip/palate: An updated meta-analysis.

Scientific reports - 30 Jan 2020

Imani Mohammad Moslem, Golchin Negin, Safaei Mohsen, Rezaei Farzad, Abbasi Hooshyar, Sadeghi Masoud, Lopez-Jornet Pia, Mozaffari Hamid Reza, Sharifi Roohollah

Abstract excerpt

Both genetic and environmental factors affect the risk of orofacial clefts. The present meta-analysis aimed to evaluate the association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and risk of nonsyndromic cleft lip/palate (NSCL/P) in cases-control studies. The PubMed/Medline, Scopus, Web of Science, and Cochrane Library databases were searched up to April 2019 with no restrictions. The...

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Identifiers

PMID: 32001764
DOI: 10.1038/s41598-020-58357-0
PMCID: PMC6992667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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