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Analysis of PTEN Methylation Patterns in Soft Tissue Sarcomas by MassARRAY Spectrometry

17 May 2013

Abstract excerpt

Soft tissue sarcomas (STSs) are a rare and fascinating group of diseases that can be subdivided into specific reciprocal translocations in STSs (SRTSs) and nonspecific reciprocal translocations in STSs (NRTSs). PTEN mutations are rare in STSs, suggesting that PTEN expression may be lost by alternative mechanisms such as methylation. In order to reveal whether aberrant PTEN methylation occurs in STSs, MassARRAY...

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PMID: 23690972
DOI: 10.1371/journal.pone.0062971

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