Article
Dismantling promoter-driven RNA polymerase II transcription complexes in vitro by the termination factor Rat1.
The Journal of biological chemistry - 5 Jul 2013
Pearson Erika L, Moore Claire L
Abstract excerpt
Proper RNA polymerase II (Pol II) transcription termination is essential to generate stable transcripts, to prevent interference at downstream loci, and to recycle Pol II back to the promoter (1-3). As such, termination is an intricately controlled process that is tightly regulated by a variety of different cis- and trans-acting factors (4, 5). Although many eukaryotic termination factors have been identified to...
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