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Article

Inappropriateness of quinolone in scrub typhus treatment due to gyrA mutation in Orientia tsutsugamushi Boryong strain.

Journal of Korean medical science - 1 May 2013

Jang Hee-Chang, Choi Su-Mi, Jang Mi-Ok, Ahn Joon-Hwan, Kim Uh-Jin, Kang Seung-Ji, Shin Jong-Hee, Choy Hyon E, Jung Sook-In, Park Kyung-Hwa

Abstract excerpt

The use of quinolone for treatment of rickettsial diseases remains controversial. Recent clinical studies suggest that quinolone is not as effective as others in patients with rickettsial diseases including scrub typhus, although the mechanism is not well understood. In this study, we evaluated the mutation in gyrA associated with quinolone resistance. We prospectively enrolled scrub typhus patients, collected...

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Share to Anti-Bacterial Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23678256
DOI: 10.3346/jkms.2013.28.5.667
PMCID: PMC3653077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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