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Article

Quinolone‐Resistant<i>Salmonella typhi</i>in Viet Nam: Molecular Basis of Resistance and Clinical Response to Treatment

1 Dec 1997

Abstract excerpt

Nalidixic acid-resistant Salmonella typhi (NARST) was first isolated in Viet Nam in 1993. Analysis of the quinolone resistance-determining region of gyrA in 20 NARST isolates by polymerase chain reaction and single-stranded conformational polymorphism yielded two novel patterns: pattern II corresponding to a point mutation at nucleotide 87 Asp-->Gly (n = 17), and pattern III corresponding to a point mutation at...

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PMID: 9431387
DOI: 10.1086/516128

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