An insulin-like growth factor-II intronic variant affects local DNA conformation and ovarian cancer survival.

doi:10.1093/carcin/bgt168

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An insulin-like growth factor-II intronic variant affects local DNA conformation and ovarian cancer survival.

Carcinogenesis - 1 Sept 2013

Lu Lingeng, Risch Evan, Deng Qian, Biglia Nicoletta, Picardo Elisa, Katsaros Dionyssios, Yu Herbert

Abstract excerpt

Insulin-like growth factor-II (IGF-II) may be a prognostic marker in ovarian cancer, and its intronic single nucleotide polymorphism (SNP) rs4320932 has been associated with risk of the disease. We determined whether rs4320932 is associated with IGF-II expression and patient survival in ovarian cancer, and explored whether the SNP variation affects DNA conformation both in the absence of and presence of...

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PMID: 23677070
DOI: 10.1093/carcin/bgt168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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