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Article

Notch signaling maintains neural rosette polarity.

PloS one - 1 Jan 2013

Main Heather, Radenkovic Jelena, Jin Shao-bo, Lendahl Urban, Andersson Emma R

Abstract excerpt

Formation of the metazoan body plan requires a complex interplay of morphological changes and patterning, and central to these processes is the establishment of apical/basal cell polarity. In the developing nervous system, apical/basal cell polarity is essential for neural tube closure and maintenance of the neural stem cell population. In this report we explore how a signaling pathway important for nervous...

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Identifiers

PMID: 23675446
DOI: 10.1371/journal.pone.0062959
PMCID: PMC3651093

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