Article
Tcf7L2 is essential for neurogenesis in the developing mouse neocortex.
Neural development - 11 May 2018
Chodelkova Olga, Masek Jan, Korinek Vladimir, Kozmik Zbynek, Machon Ondrej
Abstract excerpt
Generation of neurons in the embryonic neocortex is a balanced process of proliferation and differentiation of neuronal progenitor cells. Canonical Wnt signalling is crucial for expansion of radial glial cells in the ventricular zone and for differentiation of intermediate progenitors in the subventricular zone. We detected abundant expression of two transcrtiption factors mediating canonical Wnt signalling,...
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