Article
Tetramerization reinforces the dimer interface of MnSOD.
PloS one - 1 Jan 2013
Sheng Yuewei, Durazo Armando, Schumacher Mikhail, Gralla Edith Butler, Cascio Duilio, Cabelli Diane E, Valentine Joan Selverstone
Abstract excerpt
Two yeast manganese superoxide dismutases (MnSOD), one from Saccharomyces cerevisiae mitochondria (ScMnSOD) and the other from Candida albicans cytosol (CaMnSODc), have most biochemical and biophysical properties in common, yet ScMnSOD is a tetramer and CaMnSODc is a dimer or "loose tetramer" in solution. Although CaMnSODc was found to crystallize as a tetramer, there is no indication from the solution properties...
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