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Article

Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes.

Proceedings of the National Academy of Sciences of the United States of America - 28 May 2013

Chow Clement Y, Wolfner Mariana F, Clark Andrew G

Abstract excerpt

Natural genetic variation is a rich resource for identifying novel elements of cellular pathways such as endoplasmic reticulum (ER) stress. ER stress occurs when misfolded proteins accumulate in the ER and cells respond with the conserved unfolded protein response (UPR), which includes large-scal...

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PMID: 23667151
DOI: 10.1073/pnas.1307125110
PMCID: PMC3670321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23667151-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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