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Article

The genetic architecture of the genome-wide transcriptional response to ER stress in the mouse.

PLoS genetics - 1 Feb 2015

Chow Clement Y, Wang Xu, Riccardi David, Wolfner Mariana F, Clark Andrew G

Abstract excerpt

Endoplasmic reticulum (ER) stress occurs when misfolded proteins accumulate in the ER. The cellular response to ER stress involves complex transcriptional and translational changes, important to the survival of the cell. ER stress is a primary cause and a modifier of many human diseases. A first...

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Identifiers

PMID: 25651210
DOI: 10.1371/journal.pgen.1004924
PMCID: PMC4412289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25651210-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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