Article

The <i>Drosophila</i> metallopeptidase <i>superdeath</i> decouples apoptosis from the activation of the ER stress response

2019-04-26

Abstract excerpt

<h4>ABSTRACT</h4> Endoplasmic reticulum (ER) stress-induced apoptosis is a primary cause and modifier of degeneration in a number of genetic disorders. Understanding how genetic variation between individuals influences the ER stress response and subsequent activation of apoptosis could improve individualized therapies and predictions of outcomes for patients. In this study, we find that the uncharacterized, membr...

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Literature Corpus work: 07228a7c-14dc-581a-8cf8-85b6a150203f
DOI: 10.1101/620492

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