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Article

CYP3A5 genotype had no impact on intrapatient variability of tacrolimus clearance in renal transplant recipients.

Therapeutic drug monitoring - 1 Jun 2013

Spierings N, Holt D W, MacPhee Iain A M

Abstract excerpt

BACKGROUND: The risk of long-term chronic allograft nephropathy and graft loss after kidney transplantation is increased in patients with a high intrapatient variability in the clearance of tacrolimus. CYP3A5 genotype has a significant influence on the oral bioavailability of tacrolimus and is a potential influence on variability of exposure. METHODS: The study population consisted of 118 renal transplant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23666583
DOI: 10.1097/FTD.0b013e318289644d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CYP3A5 genotype had no impact on intrapatient variability of tacrolimus clearance in renal transplant recipients.PMID 23666583Read ↗

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