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Article

Pharmacogenetic determinants for interindividual difference of tacrolimus pharmacokinetics 1 year after renal transplantation.

Journal of clinical pharmacy and therapeutics - 1 Apr 2011

Miura M, Niioka T, Kagaya H, Saito M, Hayakari M, Habuchi T, Satoh S

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: Tacrolimus, a widely used immunosuppressive agent in organ transplantation, has a narrow therapeutic window. It has been suggested that its interaction with lansoprazole could be dependent on polymorphisms of CYP3A5 and CYP2C19. The objective of this study was to investigate how, 1 year after renal transplantation, CYP3A5 and CYP2C19 polymorphisms, biochemical parameters and...

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Identifiers

PMID: 21366650
DOI: 10.1111/j.1365-2710.2010.01163.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Pharmacogenetic determinants for interindividual difference of tacrolimus pharmacokinetics 1 year after renal transplantation.PMID 21366650Read ↗

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