Article
Association and interactions between DNA repair gene polymorphisms and adult glioma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2009
Liu Yanhong, Scheurer Michael E, El-Zein Randa, Cao Yumei, Do Kim-Anh, Gilbert Mark, Aldape Kenneth D, Wei Qingyi, Etzel Carol, Bondy Melissa L
Abstract excerpt
It is generally accepted that glioma develops through accumulation of genetic alterations. We hypothesized that polymorphisms of candidate genes involved in the DNA repair pathways may contribute to susceptibility to glioma. To address this possibility, we conducted a study on 373 Caucasian glioma cases and 365 cancer-free Caucasian controls to assess associations between glioma risk and 18 functional...
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