Article
TAM receptors in apoptotic cell clearance, autoimmunity, and cancer
10 May 2013
Abstract excerpt
Receptor tyrosine kinases, Tyro-3, Axl and Mer, collectively designated as TAM, are involved in the clearance of apoptotic cells. TAM ligands, Gas6 and Protein S, bind to the surfaces of apoptotic cells, and at the same time, interact directly with TAM expressed on phagocytes, impacting the engulfment and clearance of apoptotic cells and debris. The well-tuned and balanced actions of TAM may affect a variety of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
