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Article

The extrapituitary prolactin promoter polymorphism is associated with rheumatoid arthritis and anti-CCP antibodies in Mexican population.

Gene - 1 Aug 2013

Reyes-Castillo Zyanya, Pereira-Suárez Ana Laura, Palafox-Sanchez Claudia Azucena, Rangel-Villalobos Héctor, Estrada-Chávez Ciro, Oregón-Romero Edith, Angel-Chávez Luis Ignacio, Muñoz-Barrios Salvador, Bueno-Topete Miriam Ruth, Muñoz-Valle José Francisco

Abstract excerpt

Prolactin (PRL) is a hormone-cytokine that has been involved in autoimmunity due to its immunoregulatory and lymphoproliferative effects. It is produced by various extrapituitary sites including immune cells, under control of a superdistal promoter that contains a single nucleotide polymorphism -1149 G/T previously associated with rheumatoid arthritis (RA) susceptibility in European population. The aim of this...

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Identifiers

PMID: 23660301
DOI: 10.1016/j.gene.2013.04.068

Genes

PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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