Prolactin and Dehydroepiandrosterone Levels in Women with Systemic Lupus Erythematosus: The Role of the Extrapituitary Prolactin Promoter Polymorphism at -1149G/T.

doi:10.1155/2015/435658

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Article

Prolactin and Dehydroepiandrosterone Levels in Women with Systemic Lupus Erythematosus: The Role of the Extrapituitary Prolactin Promoter Polymorphism at -1149G/T.

Journal of immunology research - 1 Jan 2015

Treadwell Edward L, Wiley Kenneth, Word Beverly, Melchior William, Tolleson William H, Gopee Neera, Hammons George, Lyn-Cook Beverly D

Abstract excerpt

Systemic lupus erythematosus (SLE) has shown an association with high levels of prolactin, low levels of dehydroepiandrosterone (DHEA), and induction of inflammatory cytokines in the serum of patients with the disease. This preliminary study examined the relevance of a -1149G/T functional single-nucleotide polymorphism (SNP) (rs1341239) in the promoter of the extrapituitary prolactin gene in a cohort of African...

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PMID: 26583155
DOI: 10.1155/2015/435658
PMCID: PMC4637102

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