Article
The HLA-Cw*06 allele and -1149 G/T polymorphism of extrapituitary promoter of PRL gene as a possible common genetic predisposing factors to psoriasis vulgaris and psoriatic arthritis in Czech population.
Rheumatology international - 1 Apr 2013
Cibulova Anna, Zajacova Marta, Fojtikova Marketa, Stolfa Jiri, Sedova Liliana, Cejkova Pavlina, Lippert Jan, Arenberger Petr, Cerna Marie
Abstract excerpt
Psoriatic arthritis (PsA) affects approximately 30 % of patients suffering from psoriasis vulgaris (PsV), but the risk factors for its development have not been well elucidated yet. The HLA-Cw*06 allele was described as a predisposing factor to PsV. Prolactin is known as an immune response modulator, and its elevated levels present risk for PsV development. It is possible that these factors interact and together...
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