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Article

Prolactin promoter polymorphism (-1149 G/T) is associated with anti-DNA antibodies in Mexican patients with systemic lupus erythematosus.

Immunological investigations - 1 Jan 2011

Montoya-Díaz Eduardo, Cervera-Castillo Hernando, Chávez-Sánchez Luis, Legorreta-Haquet Ma Victoria, Sánchez-González Lourdes, Chávez-Rueda Karina, Blanco-Favela Francisco

Abstract excerpt

Prolactin (PRL) is a 23-kDa protein hormone that is synthesized mainly by the anterior pituitary gland. However, PRL can also be synthesized and secreted by extrapituitary tissues, particularly immune cells. A biallelic polymorphism (-1149 G/T) in the prolactin promoter has been shown to be functionally important, as modulation of prolactin expression has been associated with SLE in some populations. We have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21500962
DOI: 10.3109/08820139.2011.570402

Genes

PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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