Article
SNP set association analysis for genome-wide association studies.
PloS one - 1 Jan 2013
Cai Min, Dai Hui, Qiu Yongyong, Zhao Yang, Zhang Ruyang, Chu Minjie, Dai Juncheng, Hu Zhibin, Shen Hongbing, Chen Feng
Abstract excerpt
Genome-wide association study (GWAS) is a promising approach for identifying common genetic variants of the diseases on the basis of millions of single nucleotide polymorphisms (SNPs). In order to avoid low power caused by overmuch correction for multiple comparisons in single locus association study, some methods have been proposed by grouping SNPs together into a SNP set based on genomic features, then testing...
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