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Article

Supervised categorical principal component analysis for genome-wide association analyses.

BMC genomics - 1 Jan 2014

Lu Meng, Lee Hye-Seung, Hadley David, Huang Jianhua Z, Qian Xiaoning

Abstract excerpt

In order to have a better understanding of unexplained heritability for complex diseases in conventional Genome-Wide Association Studies (GWAS), aggregated association analyses based on predefined functional regions, such as genes and pathways, become popular recently as they enable evaluating joint effect of multiple Single-Nucleotide Polymorphisms (SNPs), which helps increase the detection power, especially...

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Identifiers

PMID: 24564304
DOI: 10.1186/1471-2164-15-S1-S10
PMCID: PMC4046680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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