Regulation of rat ornithine decarboxylase mRNA translation by its 5'-untranslated region.

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Article

Regulation of rat ornithine decarboxylase mRNA translation by its 5'-untranslated region.

The Journal of biological chemistry - 15 Jul 1990

Manzella J M, Blackshear P J

Abstract excerpt

Ornithine decarboxylase (ODC), a key enzyme in polyamine biosynthesis, is a highly inducible protein whose expression involves a complex and variable array of regulatory mechanisms. We investigated the influence of the 5'-untranslated region (5'UTR) of the rat ODC mRNA on translation of the mRNA in a cell-free system and in cultured mammalian cells. ODC mRNA containing the full-length 5'UTR was translated in...

Topics

Animals
Calorimetry
Cell Line
Cells, Cultured
Gene Expression Regulation, Enzymologic
Genes, Regulator
Growth Hormone
Humans
Kinetics
Mice
Mutation
Nucleic Acid Conformation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ornithine Decarboxylase

Plasmids

Promoter Regions, Genetic

Protein Biosynthesis

RNA, Messenger

Rats

Source

Open in PubMed

Identifiers

PMID: 2365701

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2365701-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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