Article
Regulation of rat ornithine decarboxylase mRNA translation by its 5'-untranslated region.
The Journal of biological chemistry - 15 Jul 1990
Manzella J M, Blackshear P J
Abstract excerpt
Ornithine decarboxylase (ODC), a key enzyme in polyamine biosynthesis, is a highly inducible protein whose expression involves a complex and variable array of regulatory mechanisms. We investigated the influence of the 5'-untranslated region (5'UTR) of the rat ODC mRNA on translation of the mRNA in a cell-free system and in cultured mammalian cells. ODC mRNA containing the full-length 5'UTR was translated in...
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