Article
Specific protein binding to a conserved region of the ornithine decarboxylase mRNA 5'-untranslated region.
The Journal of biological chemistry - 5 Apr 1992
Manzella J M, Blackshear P J
Abstract excerpt
An RNA gel retardation assay was used to identify one or more cellular protein(s) (ornithine decarboxylase mRNA 5'-UTR binding protein (ODCBP)) that bind specifically to a conserved region of the 5'-untranslated region (5'-UTR) of rat ornithine decarboxylase (ODC) mRNA. Ultraviolet light cross-linking demonstrated that this protein has an apparent Mr = 58,000 in mammalian cells. Treatment with the oxidizing agent...
Topics
- Animals
- Base Sequence
- Caenorhabditis
- Carrier Proteins
- HeLa Cells
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Ornithine Decarboxylase
