Article
Effects of length and mRNA secondary structure on the interaction of bovine mitochondrial ribosomes with messenger RNA.
The Journal of biological chemistry - 15 Jul 1990
Liao H X, Spremulli L L
Abstract excerpt
The mRNA for cytochrome oxidase subunit II (CoII) from bovine mitochondria binds to the small subunit of the mitochondrial ribosome in the absence of auxiliary factors. The synthetic polymer poly(U) is effective in competing with CoII mRNA for binding, although the polymer poly(A,U,G) competes very weakly. The effects of mRNA length on the interaction between the 28 S ribosomal subunit and mRNA have been examined...
Topics
- Animals
- Binding, Competitive
- Cattle
- Kinetics
- Mitochondria, Liver
- Mutation
- Nucleic Acid Conformation
- Plasmids
- Poly U
- RNA, Messenger
- Ribosomes
- Structure-Activity Relationship