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Article

Newly established human retinoblastoma cell lines exhibit an "immortalized" but not an invasive phenotype in vitro.

International journal of cancer - 15 Jul 1990

Griegel S, Hong C, Frötschl R, Hülser D F, Greger V, Horsthemke B, Rajewsky M F

Abstract excerpt

Retinoblastoma (RB), an intraocular childhood tumor occurring in a hereditary (mostly bilateral) or non-hereditary (unilateral) form, is associated with the inactivation of both alleles of a putative tumor suppressor gene (RB-I) located on chromosome 13q14. Both the process of RB development and the biological characteristics of RB cells are as yet poorly understood. We have established 7 new RBL lines (RBL13,...

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Identifiers

PMID: 2365495
DOI: 10.1002/ijc.2910460123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Newly established human retinoblastoma cell lines exhibit an "immortalized" but not an invasive phenotype in vitro.PMID 2365495Read ↗

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