Characteristics of two new retinoblastoma cell lines: WERI-Rb24 and WERI-Rb27.

doi:10.3928/0191-3913-19900701-11

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Characteristics of two new retinoblastoma cell lines: WERI-Rb24 and WERI-Rb27.

Journal of pediatric ophthalmology and strabismus - 1 Jan 2000

Sery T W, Lee E Y, Lee W H, Bookstein R, Wong V, Shields J A, Augsburger J J, Donoso L A

Abstract excerpt

From 49 eyes enucleated for retinoblastoma, two new cell lines, WERI-Rb24 (W-24) and WERI-Rb27 (W-27), were established in long-term culture (greater than 5 years). The W-24 cell line was derived from a 22-month-old boy with sporadic retinoblastoma; the W-27 cell line was derived from a 24-month-old boy with bilateral retinoblastoma. Both cell lines show abnormal mRNA transcripts corresponding to the...

Topics

Alleles
Animals
Blotting, Northern
Blotting, Southern
Child, Preschool
DNA Probes
DNA, Neoplasm
Eye Neoplasms
Humans
Infant
Male
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Transplantation

RNA, Messenger

RNA, Neoplasm

Rabbits

Retinoblastoma

Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 2391623
DOI: 10.3928/0191-3913-19900701-11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2391623-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characteristics of two new retinoblastoma cell lines: WERI-Rb24 and WERI-Rb27.PMID 2391623Read ↗

Novel miRNA-31 and miRNA-200a-Mediated Regulation of Retinoblastoma ProliferationSemantic proximity Read ↗

Expression of the RB gene under the control of MuLV-LTR suppresses tumorigenicity of WERI-Rb-27 retinoblastoma cells in immunodefective mice.Semantic proximity Read ↗

Re-characterization of established human retinoblastoma cell lines.Semantic proximity Read ↗

Mutations in the retinoblastoma gene and their expression in somatic and tumor cells of patients with hereditary retinoblastoma.Semantic proximity Read ↗

Identification of a mutation in exon 27 of the RB1 gene associated with incomplete penetrance retinoblastoma.Semantic proximity Read ↗

Characterization of NCC-RbC-51, an RB cell line isolated from a metastatic site.Semantic proximity Read ↗

Molecular mechanisms of oncogenic mutations in tumors from patients with bilateral and unilateral retinoblastoma.Semantic proximity Read ↗

Newly established human retinoblastoma cell lines exhibit an "immortalized" but not an invasive phenotype in vitro.Semantic proximity Read ↗

Isolation and characterization of a new cell line of retinoblastomaSemantic proximity Read ↗

Characterization of intragenic deletions in two sporadic germinal mutation cases of retinoblastoma resulting in abnormal gene expression.Semantic proximity Read ↗

Establishment and characterization of a novel, spontaneously immortalized retinoblastoma cell line with adherent growthSemantic proximity Read ↗

Marked differences in unilateral isolated retinoblastomas from young and older children studied by comparative genomic hybridizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.