Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Twist Overexpression Induces <i>In vivo</i> Angiogenesis and Correlates with Chromosomal Instability in Breast Cancer

1 Dec 2005

Abstract excerpt

Aggressive cancer phenotypes are a manifestation of many different genetic alterations that promote rapid proliferation and metastasis. In this study, we show that stable overexpression of Twist in a breast cancer cell line, MCF-7, altered its morphology to a fibroblastic-like phenotype, which exhibited protein markers representative of a mesenchymal transformation. In addition, it was observed that MCF-7/Twist...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16322226
DOI: 10.1158/0008-5472.can-05-0712

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Twist Overexpression Induces <i>In vivo</i> Angiogenesis and Correlates with Chromosomal Instability in Breast CancerPMID 16322226Read ↗

Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt ActivationSemantic proximity Read ↗

Twist Transcriptionally Up-regulates AKT2 in Breast Cancer Cells Leading to Increased Migration, Invasion, and Resistance to PaclitaxelSemantic proximity Read ↗

Twist alters the breast tumor microenvironment via choline kinase to facilitate an aggressive phenotype.Semantic proximity Read ↗

A twist tale of cancer metastasis and tumor angiogenesis.Semantic proximity Read ↗

High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genesSemantic proximity Read ↗

<i>ATF3</i>, an adaptive-response gene, enhances TGFβ signaling and cancer-initiating cell features in breast cancer cellsSemantic proximity Read ↗

Involvement of the transcription factor twist in phenotype alteration through epithelial–mesenchymal transition in lung cancer cellsSemantic proximity Read ↗

Twist Is Transcriptionally Induced by Activation of STAT3 and Mediates STAT3 Oncogenic FunctionSemantic proximity Read ↗

Regulation of Cancer Cell Survival, Migration, and Invasion by Twist: AKT2 Comes to InterplaySemantic proximity Read ↗

AKT-ions with a TWIST between EMT and MET.Semantic proximity Read ↗

TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma CellsSemantic proximity Read ↗

Twist mediates an aggressive phenotype in human colorectal cancer cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.