Article
Human leukocyte antigens and cellular immune responses to anthrax vaccine adsorbed.
Infection and immunity - 1 Jul 2013
Ovsyannikova Inna G, Pankratz V Shane, Vierkant Robert A, Pajewski Nicholas M, Quinn Conrad P, Kaslow Richard A, Jacobson Robert M, Poland Gregory A
Abstract excerpt
Interindividual variations in vaccine-induced immune responses are in part due to host genetic polymorphisms in the human leukocyte antigen (HLA) and other gene families. This study examined associations between HLA genotypes, haplotypes, and homozygosity and protective antigen (PA)-specific cellular immune responses in healthy subjects following immunization with Anthrax Vaccine Adsorbed (AVA). While limited...
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