Article
The role of HLA-DR-DQ haplotypes in variable antibody responses to anthrax vaccine adsorbed.
Genes and immunity - 1 Sept 2011
Pajewski N M, Parker S D, Poland G A, Ovsyannikova I G, Song W, Zhang K, McKinney B A, Pankratz V S, Edberg J C, Kimberly R P, Jacobson R M, Tang J, Kaslow R A
Abstract excerpt
Host genetic variation, particularly within the human leukocyte antigen (HLA) loci, reportedly mediates heterogeneity in immune response to certain vaccines; however, no large study of genetic determinants of anthrax vaccine response has been described. We searched for associations between the immunoglobulin G antibody to protective antigen (AbPA) response to Anthrax Vaccine Adsorbed (AVA) in humans, and...
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