Article
The Role of Polymorphism of HLA Class II Genes in Postvaccination Plague Immunity.
Bulletin of experimental biology and medicine - 1 Feb 2026
Korytov K M, Dubrovina V I, Pyatyidesyatnikova A B, Bryukhova D D, Kiseleva N O, Kuzina E A, Balakhonov S V
Abstract excerpt
We evaluated the association of alleles of human leukocyte antigen (HLA) class II genes and the levels of secretion of IL-4 and IFNγ in the blood of individuals vaccinated/revaccinated with a live plague vaccine and living in the Gorno-Altai high-mountain and Tuvinian mountain natural plague foci. Significant differences were identified in the blood content of IL-4 and IFNγ in volunteers with different variants...
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