Article
Genetic analysis of primaquine tolerance in a patient with relapsing vivax malaria.
Emerging infectious diseases - 1 May 2013
Bright A Taylor, Alenazi Thamer, Shokoples Sandra, Tarning Joel, Paganotti Giacomo M, White Nicholas J, Houston Stanley, Winzeler Elizabeth A, Yanow Stephanie K
Abstract excerpt
Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide va...
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