Article
Advanced Molecular Detection of Malarone Resistance.
Antimicrobial agents and chemotherapy - 1 Jun 2016
Talundzic Eldin, Plucinski Mateusz M, Biliya Shweta, Silva-Flannery Luciana M, Arguin Paul M, Halsey Eric S, Barnwell John W, Vannberg Fredrik, Udhayakumar Venkatachalam
Abstract excerpt
The rapid emergence of drug-resistant malaria parasites during the course of an infection remains a major challenge for providing accurate treatment guidelines. This is particularly important in cases of malaria treatment failure. Using a previously well-characterized case of malaria treatment failure, we show the utility of using next-generation sequencing for early detection of the rise and selection of a...
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