Article
A high resolution case study of a patient with recurrent Plasmodium vivax infections shows that relapses were caused by meiotic siblings.
PLoS neglected tropical diseases - 1 Jun 2014
Bright Andrew Taylor, Manary Micah J, Tewhey Ryan, Arango Eliana M, Wang Tina, Schork Nicholas J, Yanow Stephanie K, Winzeler Elizabeth A
Abstract excerpt
Plasmodium vivax infects a hundred million people annually and endangers 40% of the world's population. Unlike Plasmodium falciparum, P. vivax parasites can persist as a dormant stage in the liver, known as the hypnozoite, and these dormant forms can cause malaria relapses months or years after t...
Topics
- Adult
- Genetic Variation
- Genome, Protozoan
- Genotype
- Humans
- Malaria, Vivax
- Male
- Plasmodium vivax
- Recombination, Genetic
- Recurrence
- Sequence Analysis, DNA