Article
Exploration of Plasmodium vivax transmission dynamics and recurrent infections in the Peruvian Amazon using whole genome sequencing.
Genome medicine - 4 Jul 2018
Cowell Annie N, Valdivia Hugo O, Bishop Danett K, Winzeler Elizabeth A
Abstract excerpt
BACKGROUND: Plasmodium vivax poses a significant challenge to malaria elimination due to its ability to cause relapsed infections from reactivation of dormant liver parasites called hypnozoites. We analyzed 69 P. vivax whole genome sequences obtained from subjects residing in three different villages along the Peruvian Amazon. This included 23 paired P. vivax samples from subjects who experienced recurrent P....
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