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DNA methylation patterns of peroxisome proliferator‐activated receptor gamma gene associated with liver fibrosis and inflammation in chronic hepatitis B

6 Feb 2013

Abstract excerpt

Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor that regulates gene expression of inflammatory mediators in liver injury. Hepatitis B virus (HBV) suppresses the PPAR gamma-mediated transactivation in liver cancerous cell lines. However, the role of PPAR gamma in patients with chronic HBV infection has not fully demonstrated. Our present study was firstly to determine the...

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PMID: 23647960
DOI: 10.1111/jvh.12048

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