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Article

Expression of the peroxisome proliferator activated receptor γ gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes

10 Jul 2009

Abstract excerpt

BACKGROUND: Adipose tissues serve not only as a store for energy in the form of lipid, but also as endocrine tissues that regulates metabolic activities of the organism by secreting various kinds of hormones. Peroxisome proliferator activated receptor gamma (PPARgamma) is a key regulator of adipocyte differentiation that induces the expression of adipocyte-specific genes in preadipocytes and mediates their...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 19589179
DOI: 10.1186/1741-7007-7-38

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