Article
Association of two polymorphisms in the peroxisome proliferator-activated receptor-gamma gene with adenomyosis, endometriosis, and leiomyomata in Japanese women.
Journal of the Society for Gynecologic Investigation - 1 Jul 2006
Kiyomizu Miyo, Kitawaki Jo, Obayashi Hiroshi, Ohta Mitsuhiro, Koshiba Hisato, Ishihara Hiroaki, Honjo Hideo
Abstract excerpt
OBJECTIVE: The peroxisome proliferator-activated receptor-gamma (PPAR-gamma) is a nuclear hormone receptor that plays an important role in many diseases. This study investigated whether two polymorphisms (Pro12Ala in exon B and C161T in exon 6) of the PPAR-gamma2 gene are related to adenomyosis, endometriosis, or leiomyomata. METHODS: A total of 390 patients with adenomyosis, endometriosis, and/or leiomyomata...
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