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Article

Variations in the genes encoding the peroxisome proliferator-activated receptors alpha and gamma in psoriasis.

Archives of dermatological research - 1 Jun 2004

Mössner Rotraut, Kaiser Rolf, Matern Philipp, Krüger Ullrich, Westphal Götz A, Brockmöller Jürgen, Ziegler Andreas, Neumann Christine, König Inke R, Reich Kristian

Abstract excerpt

The three peroxisome proliferator-activated receptor (PPAR) subtypes alpha, delta (beta), and gamma belong to the group of nuclear receptors that act as ligand-activated transcription factors. Recently, expression of PPAR alpha and gamma in keratinocytes has been demonstrated, and ligands of PPAR alpha and gamma have been found to enhance epidermal maturation and protect against cutaneous inflammation. There is...

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PMID: 15083308
DOI: 10.1007/s00403-004-0463-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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