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Article

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells.

Nature medicine - 1 Jun 2013

Robbins Paul F, Lu Yong-Chen, El-Gamil Mona, Li Yong F, Gross Colin, Gartner Jared, Lin Jimmy C, Teer Jamie K, Cliften Paul, Tycksen Eric, Samuels Yardena, Rosenberg Steven A

Abstract excerpt

Substantial regressions of metastatic lesions have been observed in up to 70% of patients with melanoma who received adoptively transferred autologous tumor-infiltrating lymphocytes (TILs) in phase 2 clinical trials. In addition, 40% of patients treated in a recent trial experienced complete regressions of all measurable lesions for at least 5 years following TIL treatment. To evaluate the potential association...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23644516
DOI: 10.1038/nm.3161
PMCID: PMC3757932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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