Article
The Role of FOXP3 in Human Cancers.
Anticancer research - 1 Aug 2016
Szylberg Łukasz, Karbownik Dominika, Marszałek Andrzej
Abstract excerpt
FOXP3 transcription factor can be observed as the main component of the immune system expressed in regulatory T (Treg) cells that regulate hemostasis and self-tolerance. Moreover, the altered expression of FOXP3 was found in autoimmune diseases, benign tumors and carcinomas. Latest reports indicate that the FOXP3 gene mutation can contribute to carcinogenesis, which can be associated with immune response...
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