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Article

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs.

PLoS genetics - 1 Apr 2013

Schork Andrew J, Thompson Wesley K, Pham Phillip, Torkamani Ali, Roddey J Cooper, Sullivan Patrick F, Kelsoe John R, O'Donovan Michael C, Furberg Helena, Schork Nicholas J, Andreassen Ole A, Dale Anders M

Abstract excerpt

Recent results indicate that genome-wide association studies (GWAS) have the potential to explain much of the heritability of common complex phenotypes, but methods are lacking to reliably identify the remaining associated single nucleotide polymorphisms (SNPs). We applied stratified False Discovery Rate (sFDR) methods to leverage genic enrichment in GWAS summary statistics data to uncover new loci likely to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23637621
DOI: 10.1371/journal.pgen.1003449
PMCID: PMC3636284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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