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Article

Sex-differential selection and the evolution of X inactivation strategies.

PLoS genetics - 1 Apr 2013

Connallon Tim, Clark Andrew G

Abstract excerpt

X inactivation--the transcriptional silencing of one X chromosome copy per female somatic cell--is universal among therian mammals, yet the choice of which X to silence exhibits considerable variation among species. X inactivation strategies can range from strict paternally inherited X inactivation (PXI), which renders females haploid for all maternally inherited alleles, to unbiased random X inactivation (RXI),...

Topics

Alleles
Animals
Biological Evolution
Genes, X-Linked
X Chromosome
X Chromosome Inactivation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23637618
DOI: 10.1371/journal.pgen.1003440
PMCID: PMC3630082

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