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Article

Sexual antagonism and the evolution of X chromosome inactivation.

Evolution; international journal of organic evolution - 1 Aug 2008

Engelstädter Jan, Haig David

Abstract excerpt

In most female mammals, one of the two X chromosomes is inactivated early in embryogenesis. Expression of most genes on this chromosome is shut down, and the inactive state is maintained throughout life in all somatic cells. It is generally believed that X-inactivation evolved as a means of achieving equal gene expression in males and females (dosage compensation). Following degeneration of genes on the Y...

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PMID: 18507742
DOI: 10.1111/j.1558-5646.2008.00431.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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