Article
Influence of KIR gene copy number on natural killer cell education.
Blood - 6 Jun 2013
Béziat Vivien, Traherne James A, Liu Lisa L, Jayaraman Jyothi, Enqvist Monika, Larsson Stella, Trowsdale John, Malmberg Karl-Johan
Abstract excerpt
Natural killer (NK) cells are functionally tuned by education via killer cell immunoglobulin receptors (KIRs) interacting with HLA class I molecules. We examined the effect of KIR gene copy number variation on the education of human NK cells. The frequency of NK cells expressing a given KIR corre...
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