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Article

The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized.

Acta crystallographica. Section D, Biological crystallography - 1 May 2013

Chen Kai En, Richards Ayanthi A, Caradoc-Davies Tom T, Vajjhala Parimala R, Robin Gautier, Lua Linda H L, Hill Justine M, Schroder Kate, Sweet Matthew J, Kellie Stuart, Kobe Bostjan, Martin Jennifer

Abstract excerpt

The caspase recruitment domain (CARD) is present in death-domain superfamily proteins involved in inflammation and apoptosis. BinCARD is named for its ability to interact with Bcl10 and inhibit downstream signalling. Human BinCARD is expressed as two isoforms that encode the same N-terminal CARD region but which differ considerably in their C-termini. Both isoforms are expressed in immune cells, although...

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PMID: 23633586
DOI: 10.1107/S0907444913001558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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