Article
Genetic relationship between multiple squamous cell carcinomas arising in the oral cavity.
Head & neck - 1 Jan 2014
Montebugnoli Lucio, Leonardi Elisa, Morandi Luca, Farnedi Anna, Gissi Davide Bartolomeo, Marchetti Claudio, Tarsitano Achille, Balbi Tiziana, Gentile Luciano, Cocchi Roberto, Foschini Maria Pia
Abstract excerpt
BACKGROUND: Histological and clinical criteria are generally used to differentiate second primary tumors (SPTs) from local recurrences. The purpose of the present study was to apply mitochondrial DNA (mtDNA) D-loop analysis to differentiate SPTs from local recurrences and to validate the clinical classification. METHODS: The study population consisted of 20 consecutive patients presenting multiple oral neoplastic...
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